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It is made from three amino acids glutamine, glycine, and cysteine
There lies a narrow physiochemical window for the drug to effectively pass the stratum corneum which includes low melting point, low molecular weight of 600 Da, and water/octanol partition coefficient in the range of 13 [216]
In addition, the tricarboxylic acid cycle or electron transfer chain in the mitochondria can promote lipid ROS accumulation and is involved in cysteine-deprivation-induced ferroptosis [18]
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After reconstitution, refrigerate at 28 C