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Its authors found that use of semaglutide reduced: deaths from causes related to cardiovascular disease by 17% hospitalizations for heart failure by 76% non-fatal myocardial infarction (heart attack) by 24% the need for coronary revascularization by 24% strokes in people with diabetes by 35% deaths from any cause by 21%

The most frequent symptoms include nausea (affecting approximately 18-24% of patients), diarrhoea (15-17%), vomiting (6-10%), constipation (6-13%), abdominal pain (6-10%), and dyspepsia (5-9%)

The current FDA target action date is April 10, 2026

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