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Immunofluorescence staining was performed to assess macrophage polarization, with CD86 serving as a marker for pro-inflammatory M1 macrophages and CD206 for anti-inflammatory M2 macrophages

Glutathione and Antioxidants Glutathione also has a relationship with antioxidants such as vitamin C and E and helps to regenerate these antioxidants

The levels of SODs decline with age, whereas free radical formation increases

Carbone C, Costa A, Provensi G, Mannaioni G, Masi A (2017) The hyperpolarization-activated current determines synaptic excitability, calcium activity and specific viability of substantia nigra dopaminergic neurons

To mimic hyperglycemia in patients with T2D, we treated SC-islets with high glucose (33 mM) for 10 days

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