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For cognitive outcomes, serine (p = 0.0410) and 2-hydroxybutyrate (p = 0.0396) were increased in patients who improved, whereas no associations were observed for urinary or gait outcomes

Immunemetabolic contributions were reflected by increased tryptophan and kynurenine in patients with favorable outcomes, consistent with the established role of kynurenine metabolism in neuroimmune signaling and microglial function 60

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This equalizes pressure and makes withdrawal easier