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Its possible that they work more effectively in the brain (which in itself would be remarkable because it implies a fairly large molecule can somehow cross the blood-brain barrier)

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Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a critical prerequisite for tissue repair

Key References Olivito I, Avolio E, Minervini D, Soda T, Rocca C, Angelone T, et al

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