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Discontinuation rates due to adverse events ranged from 5.3% to 10.3% across orforglipron dose groups, compared to 2.7% in the placebo group

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Rarely, more serious side effects like pancreatitis, gallbladder problems, or thyroid issues can occur

Because GLP-1 and GIP/GLP-1 agonists slow gastric emptying, established gastroparesis can worsen on treatment

By recognizing these absorption mechanisms, we can tailor our approach to boost glutathione levels effectively