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The issue is the slow-wave sleep window that night being compromised

Longer term though the damage will mean that the person is unable to use stores to regulate their B12 which can result in susceptibility to B12 deficiency

An interesting therapeutic strategy is to induce arginine transporters (e.g., Slc7a2) in antitumor T cells, before their adoptive transfer to patients, enhancing their ability to compete for arginine in the TME, without the deleterious effects of arginine depletion for antitumor immunity [8]