Children of 5 years who weigh 50 lbs, the recommended dose should not exceed 75-100mg (1.5 to 2mg/lb)
Journal of the National Cancer Institute 118(5):903-908, 2026
Although GIP receptor activation may exert anti-emetic effects through brainstem modulation, these effects appear insufficient to completely counterbalance GLP-1 mediated emesis during early treatment and dose escalation ( In contrast, glucagon receptor activation is independently associated with nausea and vomiting through both central and peripheral mechanisms, including effects on gastric motility and autonomic signaling
doi: 10.1038/s41598-022-12086-8 99
That is the wrong expectation
When levels drop below optimal ranges, the body signals distress through fatigue, weakness, and neurological complications