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The modulation of gut dysbiosis and BA profile, as well as the improvement of the intestinal environment, may contribute to the decrease of the p-65 subunit of NF-B phosphorylation, liver F4/80 positive macrophages, inflammatory cytokine IL-1 and TNF- expression

They cost more than simple solutions but require less user preparation and may deliver better results through enhanced absorption

The combination has not been formally tested in any published clinical trial