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Chemical synthesis of macrocycles Macrocycles were synthesized by standard Fmoc solid-phase peptide synthesis (SPPS) using a Syro Wave automated peptide synthesizer (Biotage)

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However, they are also interconnected, and changes in one can affect the other

Occasionally, increased levels of glutathione can lead to a reduction in zinc, influencing the immune system and wound healing

Since the liver is critical in manufacture and detoxification of hormones, this could explain a link between women suffering heavy periods and vitamin B12 deficiency and hormone imbalance

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