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However, these citations have since been resolved, and nothing new has been cited since 2022

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On one hand, iron overload markedly enhances the accumulation of reactive oxygen species (ROS) in cerebral endothelial cells, leading to downregulation of ferroportin 1 (FPN1) and impaired iron efflux

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Timing: Best taken in the morning on an empty stomach or before training to support antioxidant levels during exercise