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The use of feminizing estrogen in combination with testosterone blocker therapy has been shown to cause any/all of the following effects: Breast growth and development Body fat redistribution Reduction of facial and body hair Muscle mass reduction Testicular size reduction Reduction in erectile function Drug Class The primary form of estrogen used is estradiol

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However, rapid changes in body composition and fluid balance during the early treatment period may cause fluctuations in creatinine levels that require careful interpretation