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Tirzepatide has also shown some promising results with up to 8% absolute reduction in liver fat content in a RCT

Abstract Accumulation of methylglyoxal (MG) contributes to glucotoxicity and mediates beta cell apoptosis

Direct costs for treating diabetes globally have been estimated to be around 860 billion USD per year, and 150 billion USD per year in the U.S

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The balance matters because it shapes the biological response