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Pegloticase (trade name Krystexxa), is also a tetrapeptide that is an intravenous drug used to treat hyperuricemia in patients that do not respond well or cannot tolerate other forms of gout treatment.

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after an initial 5-min warm up, the running speed was gradually increased to 25 m/min, which was maintained for 30 min

Two potential binding modes were selected from the docking results in hTYR (Fig

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