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Do not massage the injection site, as this can accelerate medication absorption unpredictably and may cause bruising

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chelation of the copper site by the thiol group, interference with the cellular transfer of tyrosinase to premelanosomes, which is the site of melanin synthesis and indirect inhibition of tyrosinase via its antioxidant effect as the free radical scavenging effect of it blocks the induction of tyrosinase activity caused by peroxides

a dose reduction of the sulfonylurea may be considered