3.6 Anti-inflammatory effects of GO@GSH-FA in OGD/R-induced SH-SY5Y cells To elucidate the potential anti-inflammatory role of GO@GSH-FA in ischemia-induced cellular damage, we quantitatively assessed the levels of key proinflammatory cytokines, namely Tumor Necrosis Factor- (TNF-) and, Interleukin-1 (IL-1) in SH-SY5Y cells subjected to oxygen-glucose deprivation and reoxygenation (OGD/R) and treated with GO@GSH-FA
demonstrated that ferroptosis is independent of mPTP, since ferroptosis is not affected by inactivation of CypD, a key component of mPTP 9
[17] reported that erastin works synergistically with cisplatin to inhibit OC cell growth
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Different cancer types and stages exhibit varying reliance on FAO, indicating that carnitine's role may differ based on the specific metabolic needs of the tumor
Regulatory agencies (FDA and EMA) reviewed the evidence and found no causal relationship
