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The labeled starting dose is 0.25 mg weekly for four weeks

(2020) Comparison of sublingual and intramuscular administration of vitamin B12 for the treatment of vitamin B12 deficiency in children

Vitamin B12 (cobalamin) is an essential water-soluble vitamin that plays a key role in red blood cell formation, neurological function, and DNA synthesis

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This should start to get better within forty-eight (48) hours

However, we also note that under and after tesofensine treatment, the subjects tend to be more sensitive to sucrose, detecting it correctly even at the lowest sucrose concentration (0.5%) ( Fig 11C )