tirzepatide and gastric sleeve vs. Bypass: Which Is Right for You? Bariatric Surgery vs. GLP-1 Medications:

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Inhalation may be another option, but local proliferative effects of GLP-1 in the lungs may limit such an approach

Additional details are provided in the Supplementary Information (Appendix B)

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The long-term results of this suppression are not fully characterized, though they may include alterations in the overall growth factor milieu and possible effects on tissues that respond to growth hormone independently of IGF-1