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Charles Brenner, who discovered nicotinamide riboside as an NAD+ precursor, conducted a 2016 clinical trial showing oral NR supplementation safely increased human blood NAD+ levels up to 2.7-fold [14]

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PMID 14500546

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30 Natural substrates for GSTs (Table 1) include rac-4-hydroxynonenal, a lipid peroxidation product associated with oxidative stress, and xenobiotics