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IGF-1R Binding and Downstream Signalling IGF-1 LR3 remains a full agonist of the IGF-1 receptor, with very low affinity for IGFBPs making it more potent than unmodified IGF-1 in cell culture and pre-clinical models

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Milosavljevic V, Jamroz E, Gagic M et al (2020) Encapsulation of doxorubicin in furcellaran/chitosan nanocapsules by layer-by-layer technique for selectively controlled drug delivery

Storage condition during shipping matters as well