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[Abstract]2022 Apr 26;23(9):4783

Do NOT shake vigorouslythis introduces air bubbles and mechanical stress that can fragment peptide bonds

It is a marketing nickname and does not define a standard formulation

Zang, L., Baharlooeian, M., Terasawa, M., Shimada, Y

Front Oncol (2013) 3:256

In summary, TFAM protein abundance is closely related to mtDNA content, and TFAM affects mitochondrial biosynthesis by regulating mtDNA copy number through its interaction with mtDNA (Picca and Lezza, 2015)