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This pilot study suggest that the nasal drops may be used as an alternative to injections because two thirds of ME/CFS patients reported a positive effect, accompanied by an increased number of steps, improvement of the RAND-36 physical functioning scale and the CIS20r fatigue scale, and a significant increase in serum vitamin B12 levels

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The calculator above does all of it and shows the steps

You can see these talks in places like Reddit and Drugs.com

J Cutan Aesthet Surg 2018 RCT: Topical vs Topical+Microneedling

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