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This balance between size and specificity is frequently cited as a design achievement of the original Monash research program and is one reason the molecule has endured as a reference compound across multiple laboratories

When doses are split half the daily dose and administer 2 x daily, AM & PM

Recruitment for Phase III clinical trials to assess the efficacy and safety of bepirovirsen is also underway, with results expected in early 2026 (NCT05630807 and NCT05630820)

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The result is a modest, surface-level improvement better than most skincare ingredients, but limited by the delivery method