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Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases

Nrf2-mediated therapeutic effects of dietary flavones in different diseases

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Inhibitory kinetic studies Inhibitory kinetic studies were performed in the absence and presence of increasing concentrations (0.25, 0.5, 1, and 2 mM) of IAA, IPA, and IBA

While no clinical trial has tested this combination, the anti-apoptotic and antioxidant effects of HIF-PHIs provide a strong mechanistic rationale for synergistic use with agents targeting erythrocyte apoptosis pathways (e.g., Bcl-xL upregulation or NIX inhibition)