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In PIONEER phase 3 clinical trials, Rybelsus reduced glycated hemoglobin levels (HbA1c) by 1.3% after 26 weeks compared to 0.9% with Jardiance

The critical point about side effects: they are almost always most pronounced during dose escalation and improve significantly or resolve entirely once a patient reaches a stable maintenance dose

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease

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Smaller studies have shown efficacy in reducing fine lines, enlarged pores, and uneven skin tone