The breakthrough came from Chugai Pharmaceutical, a member of the Roche Group based in Tokyo
Wang L, Xu R, Kaelber DC, et al
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KG-mediated carnitine synthesis drives DNA repair via histone acetylation
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It not only provides carbon and nitrogen sources as well as energetic substrates for cells, but also participates in signal transduction and epigenetic regulation through metabolic intermediates and key enzymatic systems