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Accepted 2025-9-4

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Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and hypoglycemia when combined with insulin or sulfonylureas

Gastrointestinal side effects including diarrhea and abdominal discomfort were the most frequently reported adverse event and necessitated discontinuation of study drug in about 12% of subjects

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