In January of 2024 we put in the requirement that you have type 2 diabetes for certain GLP-1s, and then we put in a BMI of 35 or higher for the weight loss GLP-1s
Other GLP-1 medications, such as Ozempic (semaglutide) and Mounjaro (tirzepatide), are approved for diabetes but used off-label to help patients lose weight
Since we were already working with him, he was optimized in terms of his hormones and nutrient levels, nutrition was on point, and we were working on improving sleep
Yet he also clarified that patients with a history of depression or another mood disorder whose symptoms were well controlled could be appropriate candidates for semaglutide-based drugs such as Wegovy
The hPSCs lines that demonstrated robust DE morphology at day 2 (RPMI/B27 minus insulin supplemented with 4 M CHIR99021) presented with strong nuclear staining for FOXA2 and SOX17
They can either present an irregular pigmentation or have a homogenous color pattern from bluish to reddish brown
