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It is worth noting that both disease processes involve abnormal protein accumulation, as well as sustained inflammatory changes, which, with respect to Alzheimers disease, is a known cause of neurodegeneration

The key issue facing clinicians is whether the presenting history, symptoms (or signs), radiology, and pulmonary function testing are collectively in keeping with the diagnosis of IPF or whether the findings are due to another process

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It targets dopamine-serotonin interactions in motor-reward circuits rather than the traditional raphe-cortex pathway targeted by SSRIs