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When combined with semaglutide (CagriSema), achieved 20-22% weight lossdemonstrating synergy between amylin and GLP-1 pathways

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375 Notably, ALRN-6924 does not affect cancer cells expressing mutant p53

Therefore, hepatocytes in the centrilobular area produce more NAPQI and deplete GSH faster than cells in the periportal area 25,26

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