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The medication may be allowed to reach room temperature before administration if stored under refrigeration, as cold injections may be more painful and could potentially affect absorption kinetics

These commenters expressed concern that calculating and reporting the measure creates significant administrative and financial burden and diverts limited resources from patient care without providing commensurate value or improving patient safety

and (2) A new or revised code is necessary to preserve the scientific validity of such a study, such as by preventing the unblinding of the study

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References 1] P Sikiri et al, Antiulcerogenic and anti-inflammatory effect of a new gastric juice peptide -Body Protection Compound (1991) Exp Clin Gastroenterol 1, 17-20 2] P Sikiri et al, A new gastric juice peptide, BPC