Several critical factors including real-world adherence, cost barriers, uncertainty surrounding widespread payer coverage, higher study dosages compared to real-world use, and gastrointestinal side effects affecting treatment tolerance, still remain questionable.
However, clinical observations suggest that injection may lead to better outcomes, even for gastrointestinal issues
Thirty mg (30 mg) of Span 60, cholesterol (molar ratio: 1:1), and 10 mg of LC were dissolved in a solution of methanol and chloroform in a round flask
One patient, a female individual with HS who was trying to conceive, opted for cryoinsufflation with 3-monthly treatments, with no recurrence at 6 months and no scarring or hyperpigmentation noted [121]
Others prefer morning injections so they can monitor their response throughout the day
India has over 77 million adults with diabetes as of 2025