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Ann Rheum Dis 69:12271231 Mustonen A-M, Sisnen L, Karttunen L, Julkunen P, Esrafilian A, Reijonen J, Mki J, Krger H, Arokoski J, Nieminen P (2025) Plasma amino acids reflect cartilage loss, osteoarthritis pain, functional disability, and mental health in a longitudinal study with total knee replacement, manuscript in revision

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Weeks 24 Appetite suppression becomes more noticeable Cravings begin to fade You may stop eating earlier without trying Hunger feels quieter, not gone This is often when people realize semaglutide is starting to work