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During this process, oxidized glutathione is converted back to its reduced form by the enzyme glutathione reductase and nicotinamide adenine dinucleotide phosphate (NADPH)

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The duration for which they should be continued is not specified

While oral glutathione is generally considered to be safe, there is not enough data to recommend long-term use, especially for women who are pregnant or breastfeeding, people who take prescription or over-the-counter drugs, and those who have chronic conditions, says Malhotra