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53 In both Phase 1a and 1b trials, it has been established that orforglipron does not have food or water administration restrictions and may provide a safe and effective oral treatment option for patients with T2D and other indications

This challenge is why some scientists question whether oral GLP-1 drugs can be as potent as injectables, Cavender says

Some pharmacies have convenient drop-off boxes available

people tend to eat less often, and consume smaller portions, while keeping water intake high

In one study, people who took Semaglutide GLP-1 injections along with making lifestyle changes lost an average of 15.3% of their initial body weight over 68 weeks

Wegovy and Ozempic are both GLP-1 drugs made by Novo Nordisk