Similarly, intestine-specific Znt10 KO revealed moderate systemic Mn accumulation, whereas intestine and liver double Znt10 KO resulted in severe Mn overload compared to either KO alone (Mercadante et al., 2019), suggesting that both intestine and liver ZNT10 play an essential role in Mn excretion
Anti-aging effects: Glutathione's antioxidant properties may help combat the signs of aging by reducing oxidative stress, which can contribute to wrinkles, fine lines, and other age-related skin issues
No saturation behavior for GSSG was previously detected for the fusion construct between rxYFP and ScGrx1 31 , which makes sense considering that PfGrx and many other glutaredoxins are at least two orders of magnitude more active than ScGrx1 (Table 1) 14,56
Zhang W, Li X, Xu J, Wang Y, Xing Z, Hu S, et al
Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases
N-acetylcysteine and exacerbations of chronic obstructive pulmonary disease
