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The IBS acknowledges integration into the Interdisciplinary Research Institute of Grenoble (IRIG, CEA)

This often causes chronic inflammation, which can manifest as either chronic constipation or frequent diarrhea

Macrophages are central to this process, orchestrating immune responses via cytokine secretion, phagocytosis of pathogens, apoptotic cells, and ECM debris, and facilitating tissue remodeling by releasing proteolytic enzymes and their inhibitors (135)

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Iron homeostasis and the inflammatory response