semaglutide pregnancy studies Impact of pretreatment on reproductive outcomes in women with overweight and obesity with infertility: a real-world multicenter cohort study | Reproductive Biology and Endocrinology Semaglutide Use During Pregnancy

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Lu J, Pan Q, Zhou J, Weng Y, Chen K, Shi L, et al

Users and researchers have documented effects across several domains of health and performance, though it bears mentioning that much of this evidence comes from animal studies, small human trials, or anecdotal reports rather than large-scale clinical trials

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Despite its strengths as a well-designed human intervention study, the follow-up period was relatively short, limiting conclusions regarding durability of glycemic improvements, long-term insulin resistance trajectories, or effects on clinically meaningful outcomes such as diabetes progression, medication requirements, or cardiovascular risk

Compounded semaglutide is a once-weekly injectable GLP-1 medication