Therapies in non-alcoholic steatohepatitis (NASH)
Is the Injection Procedure Painful
Phase III results for retatrutide are set to be released later in 2025 and in early 2026, but an earlier phase II trial recorded between a 7.2% and 17.5% reduction in body weight after 24 weeks, depending on the dose (7.2% on 1mg, 17.5% on 12mg), and up to a 24.2% reduction in body weight after 48 weeks for those on 12mg (-8.7% change for those on 1mg) 8
At present, there is no NICE guidance, MHRA approval, or NHS commissioning pathway for the use of GLP-1 agonists in treating alcohol use disorder
McArdle BH, Anderson MJ (2001) Fitting multivariate models to community data: a comment on distance-based redundancy analysis
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B