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For this, the probes were perfused with Ringers solution supplemented with 50 mM ethanol, at a flow rate of 5 L/min (Harvard microinfusion pump, Plato BV, Diemen, The Netherlands)

Moreover, despite the encouraging preclinical performance of 3PO, its clinical evaluation has been delayed due to several challenges, including poor solubility, low selectivity, and the necessity for high dosages to achieve therapeutic potency [49]

Among patients with migraine, various single nucleotide polymorphisms are present in non-coding mitochondrial DNA and nuclear-encoded mitochondrial proteins

The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression

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