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Renal impairment GLP-1 RAs are generally safe in patients with CKD and have demonstrated nephroprotective effects in the FLOW trial, where semaglutide significantly reduced the composite renal endpoint (hospitalization for acute kidney injury, sustained 50% decline in estimated glomerular filtration rate (eGFR), end-stage kidney disease, or renal death) in patients with type 2 diabetes and CKD [15]

We monitor the published safety data as each trial phase reports

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Safety and Interactions with Prescribed Medications Whilst natural supplements are often perceived as safe, they can cause adverse effects and interact with prescribed medications