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For individuals increasing exercise volume during weight loss, this translates to reduced soreness and faster return to productive training

This is especially relevant for people with hormone optimization protocols who may be taking thyroid medications, hormone replacement therapy, or other compounds that depend on consistent absorption patterns

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For longer injuries or chronic inflammation, extended cycles of 68 weeks may be used, followed by a taper or break

However, a significant reduction of TYK2 function makes patients more prone to infections and makes virus-resistant mouse models sensitive to virus-induced diabetes (121, 124)