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For surface downregulation, labeling was performed with SNAP-Surface-488 in MIN6B1-SNAP-GLP-1R cells before fixation, or with anti-rodent GLP-1R (2 g l 1 ) in fixed MIN6B1 and INS-1 832/3 cells plus FITC-conjugated anti-mouse secondary (F0257, Sigma, 1/200)

Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

Jacqueline Maya, M.D., from Massachusetts General Hospital-Mass General Brigham in Boston, and colleagues conducted a retrospective cohort study of 149,790 singleton pregnancies delivered between June 1, 2016, and March 31, 2025, to compare weight gain and pregnancy outcomes with and without exposure to GLP-1 RAs before or during early pregnancy

Lu SC, Lin SC

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These results indicated that a GST was required for resistance against O