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Animal experiments show that pyridoxine treatment increases the resistance of nigral dopaminergic neurons to MPTP-induced neurotoxicity in wild-type mice as well as in astrocytic Drd2 conditional knockout mice

6.4 Neuroprotective role of GLP-1 The neuroprotective effects of GLP-1 receptor agonists are receiving increasing attention in the context of sepsis, as GLP-1 can cross the bloodbrain barrier and act directly on the central nervous system

These processes include enhancing healthy liver function and normal detoxification process, and supporting bodys endogenous antioxidants, such as glutathione, which is most concentrated in the liver

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