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Mild, transient fluid retention/edema and joint or muscle pain, each reported more often on MK-677 than placebo in the same trial, linked to elevated GH and IGF-1

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21 Moreover, it was also reported that no treatment-related adverse effects were reported, as also emphasized by other studies, such as pain, swelling, or any side effects because of the injection

10.1128/JVI.78.10.5147-5156.2004