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In addition, among the fusion proteins, nGLP1-DARPin had a higher binding affinity to HSA (G = 9.2 kcal mol 1 ) compared to the mGLP1-DARPin-1 (G = 8.1 kcal mol 1 ) and mGLP1-DARPin-2 (G = 8.3 kcal mol 1 ) fusion proteins, which is comparable with the individual DARPin complexed with HSA (G = 9.6 kcal mol 1 )

TNF-, Tumor Necrosis Factor Alpha

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doi: 10.1016/j.ijporl.2010.05.008 91 ItoA.SatoT.OtaM.TakemuraM.NishikawaT.TobaS.et al