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Vitamin B12 requires an intrinsic factor-mediated active transport for absorption, therefore, lack of or inhibition of intrinsic factor results in pernicious anemia

Intervention studies There are no intervention studies in individuals with vitamin B-12 insufficiency or deficiency that have assessed the effect of folic acid supplementation on serum holoTC concentrations, but 2 studies from the 1950s suggest there is an effect

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Your body uses a form of vitamin B3 called nicotinamide to build NAD+ , the energy currency that powers mitochondria and many cell-repair processes