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The study was designed as a single-centre, home-use trial, running from December 2023 to March 2024 at PCR Corp's Manchester facility

A 5-minute rest period is observed between devices to allow absorption

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However, contrary to the findings in Egypt, a study by Indian scholars reported higher plasma GABA levels in children with ASD compared to controls (119)

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Specifically, circulating LPS binds to TLR4 on immune cell surfaces, activating the downstream NF-B signaling pathway and promoting the release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)