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Additionally, GGCT knockdown concomitantly reduced 5- oxoproline (5-OP) levels in MHCC97H cells, consistent with 5-OP being the direct enzymatic product of GGCT activity, and exogenous 5-OP rescued proliferation under Gln-deprived conditions (Fig

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Being a highly reactive radical, PLOO pulls a hydrogen atom from another PUFA, creating phospholipid hydroperoxides (PLOOH) and generating a new PL

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