Trends in prevalence and outcome of heart failure with preserved ejection fraction
Importantly, never reduce or stop insulin abruptly when starting GLP-1 therapy, as this carries a risk of diabetic ketoacidosis
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Talk to your prescribing clinician before changing your medication, calories, macros, supplements, exercise, or meal timing, especially if you have diabetes, kidney disease, gallbladder issues, a history of pancreatitis, a history of disordered eating, pregnancy, or any medical condition
Other GLP-1 medications: Mounjaro/Zepbound (tirzepatide), Trulicity, Saxenda, or others may be appropriate
DIM and indole-3-carbonol also support the detoxification and elimination of estrogen metabolites, which may be helpful for hormonal balance and protective against estrogen sensitive cancers
